Aging and longevity biology in 2026: a crash course
A sourced crash course on aging biology: hallmarks, epigenetic clocks, senolytics, reprogramming, rapamycin and who leads, as of October 2026.
Aging and longevity biology
The biology of aging and research on interventions that may extend healthy lifespan.
Longevity research tracker: aging biology milestones
A live tracker of aging and longevity research: reprogramming trials, dog lifespan drugs, senolytic and rapamycin trials, clocks and prizes.
Creatine
Creatine evidence: strength vs. cognition vs. ageing claims
Does intermittent fasting work? RCTs vs observational studies
Creatine explained: muscle, performance, safety and the brain
Intermittent fasting explained: 16:8, 5:2 and what trials show
Altos Labs
Calico Life Sciences
ER-100 (Life Biosciences' reprogramming therapy)
NIA Interventions Testing Program (ITP)
LOY-002 (Loyal's senior dog lifespan drug)
Partial reprogramming
Rapamycin and mTOR inhibition
Senolytics
TAME trial (Targeting Aging with Metformin)
Can aging be treated? Evidence, hype and the regulatory gap
The hallmarks of aging, explained
How anti-aging interventions are tested, from mice to people
How epigenetic clocks and aging biomarkers work