New and updated Life sciences pages on ContentLora.https://contentlora.com/enhttps://contentlora.com/wiki/amyotrophic-lateral-sclerosis/https://contentlora.com/wiki/amyotrophic-lateral-sclerosis/Reference page on ALS (Lou Gehrig's disease, a form of motor neurone disease): key facts, genetics, approved drugs, survival and current trials.Sun, 11 Oct 2026 00:00:00 GMTWikihealthneurotechlife-scienceshttps://contentlora.com/wiki/galleri-test/https://contentlora.com/wiki/galleri-test/Galleri is GRAIL's blood test that screens for 50+ cancer types. How it works, NHS-Galleri and PATHFINDER 2 results, accuracy and FDA status in 2026.Sun, 11 Oct 2026 00:00:00 GMTWikihealthlife-scienceshttps://contentlora.com/wiki/karl-deisseroth/https://contentlora.com/wiki/karl-deisseroth/Karl Deisseroth, Stanford psychiatrist and bioengineer, shares the 2026 Nobel Prize in medicine for optogenetics. His work, CLARITY and mental-health research.Sun, 11 Oct 2026 00:00:00 GMTWikineurotechhealthlife-scienceshttps://contentlora.com/wiki/neisseria-meningitidis/https://contentlora.com/wiki/neisseria-meningitidis/Neisseria meningitidis causes meningococcal meningitis and sepsis. Its serogroups, who is at risk, US and UK trends in 2025-2026, and vaccines.Sun, 11 Oct 2026 00:00:00 GMTWikihealthlife-scienceshttps://contentlora.com/wiki/obicetrapib/https://contentlora.com/wiki/obicetrapib/Obicetrapib is an oral CETP inhibitor that lowers LDL cholesterol. EU-approved in September 2026 as Ubeslo and Evlarco; PREVAIL outcome data are pending.Sun, 11 Oct 2026 00:00:00 GMTWikihealthmetabolic-medicinelife-scienceshttps://contentlora.com/wiki/optogenetics/https://contentlora.com/wiki/optogenetics/Optogenetics uses light-sensitive algal proteins to switch chosen nerve cells on or off. How it works, what it found, and its first clinical uses.Sun, 11 Oct 2026 00:00:00 GMTWikineurotechhealthlife-scienceshttps://contentlora.com/wiki/pcsk9-inhibitors/https://contentlora.com/wiki/pcsk9-inhibitors/PCSK9 inhibitors lower LDL cholesterol: evolocumab and alirocumab injections, twice-yearly inclisiran and the 2026 oral pill enlicitide (Lipfendra).Sun, 11 Oct 2026 00:00:00 GMTWikihealthmetabolic-medicinelife-scienceshttps://contentlora.com/wiki/yersinia-pestis/https://contentlora.com/wiki/yersinia-pestis/Yersinia pestis is the bacterium that causes plague. How it cycles in rodents and fleas, how it infects people and where it is found today.Sun, 11 Oct 2026 00:00:00 GMTWikihealthlife-scienceshttps://contentlora.com/events/als-research-tracker/https://contentlora.com/events/als-research-tracker/A dated, sourced timeline of ALS treatment milestones, from riluzole evidence to tofersen and the September 2026 ulefnersen phase 3 results.Sun, 11 Oct 2026 00:00:00 GMTDevelopinghealthlife-sciencesneurotechhttps://contentlora.com/events/cancer-screening-tracker/https://contentlora.com/events/cancer-screening-tracker/A dated, sourced timeline of 2026 cancer screening and prevention news: guideline changes, NHS-Galleri, FDA test decisions and USPSTF upheaval.Sun, 11 Oct 2026 00:00:00 GMTDevelopinghealthpolicylife-scienceshttps://contentlora.com/events/cholesterol-and-fasting-tracker/https://contentlora.com/events/cholesterol-and-fasting-tracker/Live tracker of 2026 lipid and fasting news: the new US guideline, oral PCSK9 approval, obicetrapib in the EU, the pelacarsen miss and fasting trials.Sun, 11 Oct 2026 00:00:00 GMTDevelopinghealthmetabolic-medicinelife-scienceshttps://contentlora.com/analysis/multi-cancer-early-detection-debate/https://contentlora.com/analysis/multi-cancer-early-detection-debate/NHS-Galleri missed its main goal but cut stage IV cancers. What the trial data show about multi-cancer blood tests and the views ahead of an FDA decision.Sun, 11 Oct 2026 00:00:00 GMTAnalysishealthlife-sciencespolicyhttps://contentlora.com/analysis/optogenetics-psychiatry-translation/https://contentlora.com/analysis/optogenetics-psychiatry-translation/Optogenetics won the 2026 Nobel Prize for revealing brain circuits. How far its findings are from treating depression, anxiety or addiction, and the debate.Sun, 11 Oct 2026 00:00:00 GMTAnalysisneurotechhealthlife-scienceshttps://contentlora.com/explain/als-explained/https://contentlora.com/explain/als-explained/A plain guide to ALS (Lou Gehrig's disease): what happens in the body, who gets it, how it is diagnosed, the approved drugs and the 2026 research news.Sun, 11 Oct 2026 00:00:00 GMTExplainerhealthneurotechlife-scienceshttps://contentlora.com/explain/als-treatments-guide/https://contentlora.com/explain/als-treatments-guide/What the trials and regulators found for each ALS drug: riluzole, edaravone, tofersen for SOD1-ALS, withdrawn Relyvrio, and the 2026 ulefnersen results.Sun, 11 Oct 2026 00:00:00 GMTExplainerhealthlife-sciencesneurotechhttps://contentlora.com/explain/at-home-cancer-screening-tests-buyers-guide/https://contentlora.com/explain/at-home-cancer-screening-tests-buyers-guide/FIT vs Cologuard Plus vs Shield and SimpleScreen blood tests vs Galleri: published accuracy, FDA status and prices as of October 2026. No hands-on testing.Sun, 11 Oct 2026 00:00:00 GMTExplainerhealthlife-scienceshttps://contentlora.com/explain/cancer-prevention-explained/https://contentlora.com/explain/cancer-prevention-explained/About 38% of cancers are linked to avoidable risks. Evidence on tobacco, alcohol, body weight, HPV and hepatitis B vaccines and sun protection.Sun, 11 Oct 2026 00:00:00 GMTExplainerhealthlife-scienceshttps://contentlora.com/explain/cancer-screening-explained/https://contentlora.com/explain/cancer-screening-explained/What US (USPSTF) and NHS guidelines recommend for breast, cervical, colorectal, lung and prostate cancer screening in 2026, plus benefits and harms.Sun, 11 Oct 2026 00:00:00 GMTExplainerhealthlife-scienceshttps://contentlora.com/explain/cancer-warning-signs/https://contentlora.com/explain/cancer-warning-signs/Possible early signs of cancer listed by the NCI and NHS, why most have other causes, and when to see a doctor. Sourced, plain-language guide.Sun, 11 Oct 2026 00:00:00 GMTExplainerhealthlife-scienceshttps://contentlora.com/explain/cholesterol-lowering-drugs-guide/https://contentlora.com/explain/cholesterol-lowering-drugs-guide/A sourced guide to statins, ezetimibe, bempedoic acid, PCSK9 drugs, inclisiran, oral enlicitide (Lipfendra) and obicetrapib: how they work and the evidence.Sun, 11 Oct 2026 00:00:00 GMTExplainerhealthmetabolic-medicinelife-scienceshttps://contentlora.com/explain/lipoprotein-a-explained/https://contentlora.com/explain/lipoprotein-a-explained/What Lp(a) is, why it is mostly genetic, why every adult is now advised to test once, and what the 2026 pelacarsen trial failure means for treatment.Sun, 11 Oct 2026 00:00:00 GMTExplainerhealthmetabolic-medicinelife-scienceshttps://contentlora.com/explain/meningitis-explained/https://contentlora.com/explain/meningitis-explained/What meningitis is, the bacterial and viral types, warning signs including the glass test, how it is treated and which vaccines prevent it.Sun, 11 Oct 2026 00:00:00 GMTExplainerhealthlife-scienceshttps://contentlora.com/explain/meningitis-vaccines-guide/https://contentlora.com/explain/meningitis-vaccines-guide/A sourced comparison of meningitis vaccines: what MenACWY, MenB, pentavalent MenABCWY, pneumococcal and Hib vaccines cover, who they are for and the evidence.Sun, 11 Oct 2026 00:00:00 GMTExplainerhealthlife-scienceshttps://contentlora.com/explain/plague-explained/https://contentlora.com/explain/plague-explained/What plague is, how Yersinia pestis spreads, the bubonic, pneumonic and septicaemic forms, how it is treated and where cases still occur.Sun, 11 Oct 2026 00:00:00 GMTExplainerhealthlife-scienceshttps://contentlora.com/explain/stress-and-the-body/https://contentlora.com/explain/stress-and-the-body/How the stress response works, from adrenaline and the HPA axis to cortisol, why short-term stress helps, and how chronic stress is linked to ill health.Sun, 11 Oct 2026 00:00:00 GMTExplainermental-healthhealthlife-scienceshttps://contentlora.com/wiki/alnylam-pharmaceuticals/https://contentlora.com/wiki/alnylam-pharmaceuticals/Alnylam developed the first approved RNAi drug and is a major siRNA drugmaker. Its medicines, the Amvuttra heart approval and its 2026 pipeline.Sat, 10 Oct 2026 00:00:00 GMTWikivaccines-mrnahealthlife-scienceshttps://contentlora.com/wiki/alphafold/https://contentlora.com/wiki/alphafold/AlphaFold is Google DeepMind's AI system for predicting protein and biomolecular structures. Versions, accuracy, database and limits.Sat, 10 Oct 2026 00:00:00 GMTWikiai-for-sciencelife-sciencesaihttps://contentlora.com/wiki/altos-labs/https://contentlora.com/wiki/altos-labs/Altos Labs is a cell-rejuvenation biotech launched in 2022 with US$3 billion. Its mission, sites, leadership and where it fits in aging research.Sat, 10 Oct 2026 00:00:00 GMTWikilongevitylife-scienceshealthhttps://contentlora.com/wiki/antibody-drug-conjugates/https://contentlora.com/wiki/antibody-drug-conjugates/Antibody-drug conjugates link an antibody to a toxic payload. Not immunotherapy themselves, they are increasingly paired with checkpoint inhibitors.Sat, 10 Oct 2026 00:00:00 GMTWikicancer-immunotherapyhealthlife-scienceshttps://contentlora.com/wiki/base-editing/https://contentlora.com/wiki/base-editing/Base editing rewrites a single DNA letter without cutting both strands. How it works, the first patients treated, and pivotal trials in 2026.Sat, 10 Oct 2026 00:00:00 GMTWikigene-editinglife-scienceshealthhttps://contentlora.com/wiki/biontech/https://contentlora.com/wiki/biontech/BioNTech is the Mainz-based company that co-developed the Pfizer-BioNTech COVID-19 vaccine and is now focused on mRNA cancer immunotherapy.Sat, 10 Oct 2026 00:00:00 GMTWikivaccines-mrnahealthlife-scienceshttps://contentlora.com/wiki/bispecific-t-cell-engagers/https://contentlora.com/wiki/bispecific-t-cell-engagers/Bispecific antibodies bind two targets at once, either linking T cells to tumours or pairing PD-1 with VEGF blockade. Approvals and 2026 trial results.Sat, 10 Oct 2026 00:00:00 GMTWikicancer-immunotherapyhealthlife-scienceshttps://contentlora.com/wiki/brain-initiative/https://contentlora.com/wiki/brain-initiative/The US BRAIN Initiative funds neurotechnology and brain-mapping research. Its 2013 launch, budget swings from $680 million to $320 million, and 2026 rebound.Sat, 10 Oct 2026 00:00:00 GMTWikineurotechlife-scienceshealthhttps://contentlora.com/wiki/cagrisema/https://contentlora.com/wiki/cagrisema/CagriSema combines the amylin analogue cagrilintide with semaglutide. Novo Nordisk's REDEFINE results, the miss against tirzepatide and its FDA review.Sat, 10 Oct 2026 00:00:00 GMTWikimetabolic-medicinehealthlife-scienceshttps://contentlora.com/wiki/calico-life-sciences/https://contentlora.com/wiki/calico-life-sciences/Calico is the aging research company Google announced in 2013. Its mission, AbbVie partnership, pipeline and 2026 milestones.Sat, 10 Oct 2026 00:00:00 GMTWikilongevitylife-scienceshealthhttps://contentlora.com/wiki/car-t-cell-therapy/https://contentlora.com/wiki/car-t-cell-therapy/CAR-T cell therapy: engineered T cells approved for blood cancers since 2017. Approvals, safety rules, the 2026 solid-tumour first and what comes next.Sat, 10 Oct 2026 00:00:00 GMTWikicancer-immunotherapyhealthlife-scienceshttps://contentlora.com/wiki/casgevy/https://contentlora.com/wiki/casgevy/Casgevy is the first approved CRISPR medicine, an edited stem cell therapy for sickle cell disease and beta-thalassemia. Approvals, data and status.Sat, 10 Oct 2026 00:00:00 GMTWikigene-editinghealthlife-scienceshttps://contentlora.com/wiki/cell-free-protein-synthesis/https://contentlora.com/wiki/cell-free-protein-synthesis/Cell-free systems express genes in a tube using extracted cellular machinery. Yields, uses in circuit prototyping and on-demand production, and 2026 funding.Sat, 10 Oct 2026 00:00:00 GMTWikisynthetic-biologylife-sciencessciencehttps://contentlora.com/wiki/cepi/https://contentlora.com/wiki/cepi/CEPI funds vaccines against epidemic threats and leads the 100 Days Mission. Its role in mRNA and pandemic preparedness, and its 2027-2031 plan.Sat, 10 Oct 2026 00:00:00 GMTWikivaccines-mrnahealthlife-scienceshttps://contentlora.com/wiki/crispr-cas9/https://contentlora.com/wiki/crispr-cas9/CRISPR-Cas9 is the RNA-guided DNA-cutting tool behind modern gene editing and the first approved CRISPR medicine. Origins, uses and limits.Sat, 10 Oct 2026 00:00:00 GMTWikigene-editinglife-scienceshealthhttps://contentlora.com/wiki/crispr-therapeutics/https://contentlora.com/wiki/crispr-therapeutics/CRISPR Therapeutics is the Swiss-based gene-editing company behind Casgevy with Vertex, now running in vivo CRISPR trials in heart and liver disease.Sat, 10 Oct 2026 00:00:00 GMTWikigene-editinghealthlife-scienceshttps://contentlora.com/wiki/eli-lilly/https://contentlora.com/wiki/eli-lilly/Eli Lilly makes tirzepatide (Mounjaro, Zepbound) and the GLP-1 pill Foundayo, and is developing retatrutide. Its 2026 results, pipeline and pricing.Sat, 10 Oct 2026 00:00:00 GMTWikimetabolic-medicinehealthlife-scienceshttps://contentlora.com/wiki/enzymatic-dna-synthesis/https://contentlora.com/wiki/enzymatic-dna-synthesis/Enzymatic DNA synthesis uses polymerases instead of phosphoramidite chemistry to write DNA. Its length claims, pricing and 2026 commercial status.Sat, 10 Oct 2026 00:00:00 GMTWikisynthetic-biologylife-sciencessciencehttps://contentlora.com/wiki/er-100/https://contentlora.com/wiki/er-100/ER-100 is the first partial epigenetic reprogramming therapy tested in people, in a Phase 1 trial in glaucoma and NAION. Design, early data and caveats.Sat, 10 Oct 2026 00:00:00 GMTWikilongevitylife-scienceshealthhttps://contentlora.com/wiki/ginkgo-bioworks/https://contentlora.com/wiki/ginkgo-bioworks/Ginkgo Bioworks sells cell engineering services, lab automation and datasets. Its 2026 finances, restructuring and pivot to automation and government work.Sat, 10 Oct 2026 00:00:00 GMTWikisynthetic-biologylife-sciencessciencehttps://contentlora.com/wiki/immune-checkpoint-inhibitors/https://contentlora.com/wiki/immune-checkpoint-inhibitors/Checkpoint inhibitors such as pembrolizumab release immune brakes like PD-1 and CTLA-4. How they work, who responds, side effects and 2026 approvals.Sat, 10 Oct 2026 00:00:00 GMTWikicancer-immunotherapyhealthlife-scienceshttps://contentlora.com/wiki/in-vivo-car-t/https://contentlora.com/wiki/in-vivo-car-t/In vivo CAR-T aims to make CAR-T cells inside the body with one infusion, skipping cell manufacturing. Early 2025-2026 myeloma data, safety and limits.Sat, 10 Oct 2026 00:00:00 GMTWikicancer-immunotherapyhealthlife-scienceshttps://contentlora.com/wiki/intellia-therapeutics/https://contentlora.com/wiki/intellia-therapeutics/Intellia Therapeutics develops in vivo CRISPR therapies. Lonvo-z for hereditary angioedema is under FDA review; nex-z trials resumed after a 2025 hold.Sat, 10 Oct 2026 00:00:00 GMTWikigene-editinghealthlife-scienceshttps://contentlora.com/wiki/interventions-testing-program/https://contentlora.com/wiki/interventions-testing-program/The NIA Interventions Testing Program tests candidate anti-aging compounds in genetically diverse mice at multiple sites. Its design and key results.Sat, 10 Oct 2026 00:00:00 GMTWikilongevitylife-scienceshealthhttps://contentlora.com/wiki/intismeran-autogene/https://contentlora.com/wiki/intismeran-autogene/Intismeran autogene is Moderna and Merck's personalised mRNA cancer therapy. What it is and its 2026 phase 3 melanoma results.Sat, 10 Oct 2026 00:00:00 GMTWikivaccines-mrnahealthlife-sciences